Center for Applied Genomics

Recent discoveries in epigenetics could soon make a clinical difference for children with attention-deficit/hyperactivity disorder, autism spectrum disorder, and other conditions, according to an expert.
Article by: Family Practive News; April 30, 2012
 

CAG scientists have discovered two gene variants that appear to play a critical role in the development of common childhood obesity, according to a large genetic study released Sunday. The discovery could eventually lead to treatments and specific lifestyle advice for heavy children.
Article by: USA Today; April 09, 2012
 

Gene Chip, Invented by Children’s Hospital of Philadelphia Scientist, Pinpoints New Target to Prevent Heart Disease.
Article by: Forbes; March 15, 2012
 

In the largest genetics study of Type 2 diabetes, the Children's Hospital of Philadelphia said the findings could point to biological targets for developing more effective drugs for the disease, which accounts for most of the nearly 26 million people living with diabetes in the United States.
Article by: DSN News; February 16, 2012
 

Researchers at The Children’s Hospital of Philadelphia have located a specific genetic variation that may affect about 10% of ADHD patients, and the finding could enable doctors to individualize treatment.
Article by: EMax; December 15, 2011
 

Extended studies identified over 200 genes interacting with glutamate receptors that were collectively affected by CNVs, sug­gesting that up to 10% of individuals with ADHD may be enriched for GRM network variants.
Article by: Medline Plus; December 5, 2011
 

This week, the Children’s Hospital of Philadelphia announced that it has become BGI’s newest partner, teaming up with the institute to sequence and analyze the genomes of each of its patients.The aim is to discover genes underpinning rare and common pediatric diseases.
Article by: Forbes; November 11, 2011
 

New research published Molecular Autism used genome wide association study (GWAS) data to find a variation in the gene for transducin ß-like 1X-linked (TBL1X) which is associated with increased risk of ASD in boys.
Article by: Science Daily; November 3, 2011
 

The first clinical uses of whole-genome sequencing show just how challenging it can be.
Article by: Nature; October 5, 2011
 

Type 1 diabetes affects 200 million people worldwide. A research team led by CAG Director, Hakon Hakonarson, have discovered new genes that will help them better understand the origin of this complex disorder.
Article by: CBS News; October 4, 2011